CUL7 and arterial occlusion: Transgenic expression of a dominant-interfering Cul7 mutant (Cul7MHC-1152 stop mice) resulted in a marked induction of CM cell cycle activity at the infarct border zone 4 weeks after permanent coronary artery occlusion and was associated with an induction of cardiomyocyte DNA synthesis in the interventricular septa of infarcted hearts [14].