AFP and hepatocellular carcinoma: Although several clinical predictors of prognosis of HCC treated with RFA as first-line therapy, such as ChildPugh class, alphafetoprotein (AFP) level and age have been reported, there is no consensus.[6,7] Recently, several preoperative imaging features of HCC have been used to predict early recurrence of HCC following hepatic resection, but preoperative radiological features are rarely used to predict the prognosis of HCC treated with RFA.