The presence of mediastinal adenopathy may be the only imaging change in pulmonary TB in HIV-infected patients with CD4+ cell counts below 200 cells/μL.[22,23] It is estimated that 60% to 68.8% of TB cases in patients in the last stage of HIV infection are associated with mediastinal/hilar adenopathy.[24,25]. This evidence concerns the gene CD4 and pulmonary tuberculosis.