GBS is an autoimmune neurological disorder characterized by limb weakness, weakening, or disappearance of tendon reflexes and progression over several weeks followed by gradual recovery.[2] Our results showed that serum IL-36α and IL-36γ levels were significantly elevated in patients with GBS during the acute phase compared to the HC group, and these cytokines tended to decrease in the recovery phase. Here, IL36G is linked to Guillain-Barre syndrome.