SYNJ1 and nervous system disorder: Missense and nonsense mutations in the 5PPase domain of Synj1 have been associated with several neurological disorders, such as early-onset seizures and early-onset atypical Parkinson’s disease (Hardies et al., 2016; Xie et al., 2019; Taghavi et al., 2018; Hong et al., 2019; Bouhouche et al., 2017).