PODXL and cancer: Apart from stimulating the exosomal transfer of miRNAs, mutp53 was also shown to confer pro-migratory and pro-invasive attributes to tumor and non-tumor cells by altering the exosomal expression levels of podocalyxin (PODXL), a sialomucin and glycocalyx component that functions as a transmembrane adhesion receptor associated with cancer aggressiveness [107].