TWIST2 and cancer: As expected, genes associated with the epithelial-like phenotype (CDH1), cell lineage determination and differentiation (TWIST2), regulation of cell survival and proliferation, stem cell maintenance (KIT), cellular communication, and the normal development and function of the nervous system (ALK), cell proliferation, motility, and invasive activity promoting cancer metastasis (PTP4A3), and cell cycle regulation (CCND2) were up-regulated.