CYP2R1 and systemic lupus erythematosus: No studies regarding CYP2R1 (rs10541657) or CYP27B1 (rs10877012) SNPs were found, and we observed that the F allele, FF, and Ff genotypes in FokI (rs2228570), as well as the B allele, BB, and Bb genotypes in BsmI (rs1544410), were associated with genetic risk to SLE.