VDR and systemic lupus erythematosus: Nonetheless, these SNPs were evaluated in haplotypes also considering to FokI (rs2228570), the tAf haplotype (also interpreted as fAt according to the order of location of the polymorphic sites in VDR) was associated with a higher risk to SLE (OR = 2.7 [95% CI, 1.1–6.8], p = 0.025), along with FokI (rs2228570) Ff genotype (OR = 1.8 [95% CI, 1.1–3.1], p = 0.02) and the TaqI (rs731236) Tt genotype (OR = 2.8 [95% CI, 1.6–5], p = 0.0002) [95].