In various populations of SLE, RA, and MS patients, the BsmI (rs1544410), ApaI (rs7975232), and TaqI (rs731236) VDR SNPs were described with a strong LD [94,95], which infers that the alleles of these three polymorphisms could segregate into haplotypes from one generation of persons to another. Here, VDR is linked to systemic lupus erythematosus.