In another Egyptian study population of SLE and osteoarthritis patients vs. CS, the FokI (rs2228570) ff genotype and the fb haplotype of the FokI (rs2228570) and BsmI (rs1544410) VDR SNPs were associated with a higher SLE disease activity and were significantly in higher frequency in SLE patients than osteoarthritis patients and CS [97]. Here, VDR is linked to osteoarthritis.