The CYP2R1 (rs10541657) GG genotype was associated with lower calcidiol levels in RA patients from Spain [121], and we observed a tendency about the presence of FokI (rs2228570) FF and Ff genotypes, BsmI (rs1544410) bb genotype, TaqI (rs731236) TT genotype with RA genetic risk; however, no clear tendency was observed in ApaI (rs7975232) VDR SNPs and RA. Here, VDR is linked to rheumatoid arthritis.