There were no significant differences between the concentration of purified antibodies (p = 0.063) in RA and the healthy blood donors group, but the absorbance of the reaction was correlated with the concentration of purified antibodies samples (LPS O3 r = 0.96; collagen type I r = 0.85; Lys-GalA = 0.56; Thr-GalA = 0.92, p < 0.05). This evidence concerns the gene GLA and rheumatoid arthritis.