In A375 melanoma stem-like cells, miRNA expression profiling has shown an overexpression of miR-125b, -100, and -199-5p, while miR-513a-5p and -185 are underexpressed, with miR-125b being considered as the determinant candidate of melanoma progression, through its ability to target the neural precursor cell expressed, developmentally down-regulated 9 (NEDD9) gene [114]. This evidence concerns the gene NEDD9 and melanoma.