Indeed, and consistently with previous reports on CT genes [38], the expression of the meiosis specific gene HORMAD1 [39,40], the MAGE-A gene family [41], and the sperm specific cytochrome c oxidase COX6B2 [42,43], we found that a high GC signature score correlates with poor prognosis in lung adenocarcinoma. The gene discussed is COX6B2; the disease is lung adenocarcinoma.