CSF2 and neoplasm: Vaccines based on tumor cells are often composed of syngeneic, allogeneic or autologous irradiated freshly isolated primary tumor cells, modified, or not, with cytokines such as GM-CSF (GVAX is a vaccine consisting of mitotically inactivated tumor cells genetically modified with the cytokine genome GM-CSF, which has an immunostimulatory effect) or viruses such as the Newcastle disease virus.