Another study reported that a modified alternate-day energy restriction (alternating a fasting day with a restriction of 70% of energy requirement and non-fasting day ad libitum) for 8 weeks led to a significant reduction of liver steatosis and fibrosis grades, BMI, and ALT compared to an usual habitual diet (i.e., no intervention) [90]. The gene discussed is GPT; the disease is Hepatic steatosis.