Nonetheless, we were not able to demonstrate an association between myelin responsiveness and the primordial MS-associated risk alleles of the HLA-DR15 haplotype, consisting of HLA-DRB1*15:01, HLA-DQA1*01:02 and HLA-DQB1*06:02 [15]. Here, HLA-DRB1 is linked to myeloid sarcoma.