In the Nakanishi study, the ApcMin/+ model of intestinal polyposis was crossed with a Dclk1Cre-ERT mouse to generate lineage tracing (ApcMin/+;Dclk1Cre-ERT;R26LacZ) and diptheria-toxin receptor TC-specific deletion (ApcMin/+;Dclk1Cre-ERT;iDTR) mice. Here, ELF3 is linked to gastrointestinal polyp.