POU2F3 and pancreatic neoplasm: In pancreatic tumors, it has recently been shown that immune cell-derived IL-17 regulates the development of TCs via increased expression of DCLK1, POU domain class 2 transcription factor 3 (POU2F3), aldehyde dehydrogenase 1 family member A1 (ALDH1A1), and IL17RC [48].