SERPING1 and hyperinsulinemic hypoglycemia, familial, 4: Short-term prophylaxis with C1-INH concentrate administration up to 6 hours before the procedure or having a dose of C1-INH concentrate available in the delivery room is recommended to prevent a possible bout of edema during childbirth in women with HAE with C1-INH deficiency, but not for HAE with normal C1-INH.3, 7