MTOR and myeloid sarcoma: For example, a mouse model of MS shows reduced mTOR activity in neurons and CBD treatment restored mTOR signalling (Giacoppo, Pollastro, Grassi, Bramanti, & Mazzon, 2017), yet mTOR is activated in immune cells in this disease and reducing mTORC1 signalling provides a therapeutic mechanism (Mammana et al., 2018).