We found that overexpressed CDK5R1 was significantly associated with tumor status (OR = 2.28 for with tumor vs. tumor free, P=0.00), new tumor event (OR = 1.95 for yes vs. no, P=0.00), clinical stage (OR = 2.10 for III-IV vs. I-II, P=0.00) and topography (OR = 2.08 for T3-4 vs. T1-2, P=0.00). Here, CDK5R1 is linked to neoplasm.