CDK5 and neoplasm: Univariate analysis for OS with Cox regression model showed that poor OS had prominently correlation with CDK5R1 expression (high vs. low; P=0.033, HR = 2.0 (95% CI [1.1–3.9])), new tumor event (yes vs. no; P=0.012, HR = 3.0 (95% CI [1.3–7.0])), tumor status (with tumor vs. tumor free; P=0.001, HR = 4.0 (95% CI [1.8–9.2])), CDK5 expression (high vs. low; P=0.032, HR = 2.4 (95% CI [1.1–5.2])), CDC25B expression (high vs. low; P=0.005, HR = 3.1 (95% CI [1.4–6.8])) (Table 3).