It has been reported that LINC00460, a novel lncRNA, is essential for the onset and the development of multiple cancers such as head and neck squamous cell carcinoma [16], hepatocellular carcinoma [17], lung cancer [18], colorectal cancer [19], etc. However, the role of LINC00460 in PAAD progression has not been well clarified. This evidence concerns the gene LINC00460 and head and neck squamous cell carcinoma.