Therefore, the study aimed at analysing differential expression of relatively neglected inflammatory-immune responsive genes LTA, LTB, TNFSF4, TNFSF11, TNFSF13, TNFSF13B, TNFRSF11B and GFPT1/GFA in inflamed gingival tissues of bronchiectasis patients compared to systemically healthy chronic periodontitis counterparts. The gene discussed is TNFSF4; the disease is bronchiectasis.