Interestingly, the NF-κB, TNFR1, TNFR2, and IL-6 pathways related to inflammation; the p53 and FAK pathways related to cancer growth; and the G2/M checkpoint pathway related to the cell cycle were found to be more important to elucidate the mechanism of PZH and were further validated in the following experiments. Here, TNFRSF1A is linked to cancer.