SIVA1 and hepatocellular carcinoma: According to the above analysis, PLB could inhibit proliferation and induce autophagy and apoptosis of HCC, and the mechanism was likely to be related to prestrain angiogenesis, ROS level, autophagy gene and protein expression levels, caspase-3 protein level, vimentin caspase-3, and SIVA/mTOR signaling pathway.