In Chen's gastric dataset, CBX4 was overexpressed in gastric intestinal-type adenocarcinoma (fold − change = 1.783 and P = 2.55E − 17), gastric mixed adenocarcinoma (fold − change = 1.955 and P = 3.03E − 06), and diffuse gastric adenocarcinoma (fold − change = 1.730 and P = 4.23E − 04). Here, CBX4 is linked to diffuse gastric adenocarcinoma.