BRD4 and cancer: Indeed, inhibition of BRD4 by inhibitors revealed the involvement of BRD4 in various cancers in animal models (Zuber et al., 2011; Herrmann et al., 2012; Lockwood et al., 2012; Ott et al., 2012; Asangani et al., 2014; Segatto et al., 2017).