Thirdly, some lymphomas reveal hallmark cytogenetic abnormalities, such as: t(8, 14) (q24;q32), or its variants, was demonstrated in most cases of BL (8, 21); MYC rearrangement accompanied with BCL2 or BCL6 gene rearrangement was detected in “double hit” lymphomas (DHL). The gene discussed is BCL2; the disease is Burkitt lymphoma.