It has been found that the expression levels of HOTTIP (HOXA distal transcript antisense RNA), MALAT1 (metastasis associated lung adenocarcinoma transcript 1), and HULC (hepatocellular carcinoma up-regulated long non-coding RNA) are elevated in chemotherapy-resistant gastric cancer cell lines and tumor tissues (YiRen et al., 2017; Xin et al., 2019; Zhao et al., 2020). The gene discussed is MALAT1; the disease is hepatocellular carcinoma.