Moreover, a six-gene risk score model (ZNF486, EPHA5, RP11.326C3.15, DUSP6, DUSP10, and TRIAP1) for the prognostic prediction of PI-treated myeloma patients was developed by the random survival forest variable hunting (RSF-VH) algorithm (Liu et al., 2019). This evidence concerns the gene ZNF486 and plasma cell myeloma.