Numerous studies have suggested that SOX10 is highly expressed in melanoma (Cronin et al., 2018), breast cancer (Feng et al., 2017), bladder cancer (Yin et al., 2017), ovarian and epithelial tumors (Kwon et al., 2016), whereas its tumorigenic roles have not been clearly elucidated yet (Sun et al., 2014; Laurette et al., 2015; Kaufman et al., 2016; Seberg et al., 2017). This evidence concerns the gene SOX10 and urinary bladder cancer.