FBXL19, the complementary gene of FBXL19-AS1, was also up-regulated in HCC and found to be negatively correlated with macrophage M1 (p = 0.028) in the high FBXL19 group of HCC tissues base on TCGA LIHC dataset (Figure 3B). The gene discussed is FBXL19; the disease is hepatocellular carcinoma.