Among them, pathways that might be related to HCC including mTOR signaling pathway, Hedgehog signaling pathway, hepatitis B, hepatitis C, p53 signaling pathway, Wnt signaling pathway, GnRH signaling pathway, ErbB signaling pathway, PI3K-Akt signaling pathway, MAPK signaling pathway, and so on. This evidence concerns the gene AKT1 and hepatitis B virus infection.