Indeed, HIV-DLBCL has GCB DLBCL lesions such as gains of 2p, 7q, and 12q, as well as losses of 1p, but it also carries 3q and 18q gains, commonly associated with ABC DLBC, and lacks the 10q deletions involving PTEN (30). The gene discussed is PTEN; the disease is diffuse large B-cell lymphoma.