Despite their phenotypic reminiscence of post-GC B-cells (29, 68), PT-DLBCL have a pattern of DNA gains and losses that is different from ABC DLBCL, lacking gains of 3q and 18q (BCL2, NFATC1) and losses of 6q (PRDM1 and TNFAIP3) (57). This evidence concerns the gene TNFAIP3 and diffuse large B-cell lymphoma.