PSMG3 and cancer: According to reports, BCL11A acts as a carcinogenic gene for a variety of human cancers, such as breast cancer (60), laryngeal squamous cell carcinoma (61), high-risk neuroblastoma (62), non-small cell lung cancer (63) etc. In addition, the expression of PSMG3-AS1 in breast cancer tumor tissues and cell lines was increased, and PSMG3-AS1 as a sponge of miR-143-3p enhanced the proliferation and migration ability in the pathogenesis of breast cancer (64).