There was a positive correlation between PIK3CA and CUX1expression (P < 0.001) based on R2 Database (Tumor Bladder-Orntoft-60-MAS5.0-U133A, http://hgserver1.amc.nl/cgi-bin/r2/main.cgi) (Figure 3A). The gene discussed is PIK3CA; the disease is neoplasm.