ASGPR, expressed exclusively on hepatocytes, normally binds nonreducing terminal β‐d‐galactose (d‐Gal) or N‐acetylgalactosamine (GalNAc) residues with high affinity.[22] So far, the visualization of liver fibrosis progression by quantification of ASGPR levels with a 18F‐labeled monovalent galactose derivative via single‐photon emission computed tomography has been reported in a single study.[23] However, high concentrations of the tracer in the μM range were necessary due to the low affinity of the tracer to the receptor. The gene discussed is ASGR1; the disease is Hepatic fibrosis.