Ex vivo images of the organs also showed that the fluorescence of Q‐annexin V was selectively turned on in tumor tissues only after anti‐PD‐1/4‐1BB treatment, while strong fluorescence of annexin V‐Alexa647 was found in tumor tissues and kidneys before and after anti‐PD‐1/4‐1BB treatment (Figure 7c). Here, ANXA5 is linked to neoplasm.