There was limited evidence that anxiety levels are higher in patients with PFP (Weir et al., 1995; Bradbury, Simons & Sanders, 2006; Fu, Bundy & Sadiq, 2011; Silva et al., 2011; Walker et al., 2012; Pouwels et al., 2014; Sun et al., 2015; Worrack et al., 2018; Díaz-Aristizabal et al., 2019; Muhammad Kassim, Abdullahi & Sammani Usman, 2019). Here, PRF1 is linked to Anxiety.