TP53 and cervical carcinoma: Currently, a large number of gene mutations have been proved to be related to the pathogenesis of cervical cancer, which can be used as biomarkers for early detection, like DNA mutations occurring on the oncogenes tumor protein 53 (TP53) (Crook et al., 1992), phosphatase and tensin homolog (PTEN) (Yang et al., 2015).