In our patient, the pathologist was able to diagnose PC thanks to the presence of multiple full-thickness capsular infiltration foci (Figure 1) and a venous vascular invasion focus (Figure 2), highlighted by immunohistochemical staining for CD31 (Figure 3), but, as we reported earlier, no fibrosis or necrosis was found. This evidence concerns the gene PECAM1 and pachyonychia congenita.