DUSP1 and obesity due to melanocortin 4 receptor deficiency: In addition, the m6A methylation levels of genes related to these diseases also changed after DBS; such changes occurred with Slc1a6 (an OCD-associated gene [67,68]: hypermethylation), Kcnj11 (an obesity-associated gene: hypermethylation) [69,70], and Dusp1 (an addiction-associated gene: hypermethylation) [66] (Supplementary Tables S4 and S5).