AKT1 and cancer: KEGG analysis provided us with even more interesting results: up-regulated DEGs may inextricably linked to many other diseases, including many neurodegenerative diseases, human papillomavirus (HPV) infection, non-alcoholic fatty liver disease (NAFLD); down-regulated DEGs not only affected some classic cancer-related biological processes, such as PI3K-Akt pathway and focal adhesion, but may also participate in the onset of cardiomyopathy.