WNT9B, encodes the secreted signaling proteins (Garriock et al., 2007), is significantly associated with systolic blood pressure (Hoffmann et al., 2017), which is further related to the risk of CAD (Turner et al., 1998) and CKD (Jafar et al., 2003). The gene discussed is WNT9B; the disease is coronary artery disorder.