For example, ANRIL (anti-sense ncRNA) in the INK4 locus, which is increasingly expressed in prostate cancer, affects the specific repression of the tumor suppressor locus, which encodes p15 (also known as INK4B), p14 (also known as ARF), and p16 (also known as INK4A). This evidence concerns the gene CDKN2B and prostate carcinoma.