They found the total protein concentration to be increased in the inflamed aqueous of both uveitis models, as compared to the naïve aqueous, including calprotectin (a heterodimer of S100A8 and S100A9) and apolipoprotein E. Apolipoprotein E had higher levels in EAU than PMU in the aqueous. The gene discussed is APOE; the disease is uveitis.