On the other hand, published data using a deep dermatophytosis model in TLR-2 deficient mice subcutaneously infected with T. mentagrophytes demonstrated that fungal interaction with TLR-2 suppresses the inflammatory response of peritoneal macrophages and the production of IL-17, IL-10 and IFN-γ (interferon-gamma) by splenocytes (56). This evidence concerns the gene IFNG and dermatophytosis.