In addition, in an adoptive transfer experiment in which mice received a high quantity of P14 CD8+ T cells (3x106/mouse) before LCMV infection showed these cells to be more strongly activated in WT mice as soon as 24h after infection (CD25+ P14 T cells = 69.2% in IL4I1-/- mice versus 48.2% in WT mice). Here, CD8A is linked to infection.