ITGAM and breast cancer: Even as the same subtype of breast cancer, they could still be immuno-subtyped into neutrophil-enriched subtype (NES, CD11b+ Ly6Cmid Ly6G+) or macrophage-enriched subtype (MES, CD11b+ Ly6G- Ly6C- F4/80+) according to their preference to recruit TANs and TAMs.