Human umbilical cord MSCs promote the EMT, invasion, and migration of A549 lung cancer cells via MSC-derived exosomes, while silencing TGF-β1 expression in MSCs can inhibit the EMT-promoting effect of MSCs on A549 cells via MSC-derived exosomes (Zhao et al., 2018). The gene discussed is TGFB1; the disease is lung carcinoma.