PD pathology includes the loss of dopaminergic neurons of the substantia nigra, which results in motor deficits (Braak et al., 2003; Ouchi et al., 2005; Nemani et al., 2010; Wang et al., 2015) and Lewy bodies, which are protein aggregates composed of fibrillar pathogenic α-synuclein (Giasson et al., 1999, 2002; Harding and Halliday, 2001; Mackenzie, 2001; Braak et al., 2003; Feng et al., 2010; Uversky, 2010; Vekrellis et al., 2011; Rockenstein et al., 2014; Shameli et al., 2016). This evidence concerns the gene SNCA and Parkinson disease.