However, in some other tumours (such as oesophageal cancer, gastric cancer, medulloblastoma, bladder cancer, pancreatic cancer, colorectal cancer and pancreatic duct cancer), KLF4 plays a role in inhibiting the growth and proliferation of tumour cells.35, 36, 37, 38, 39, 40, 41, 42. The gene discussed is KLF4; the disease is familial pancreatic carcinoma.