There are a number of reports that focus on the protumorigenic function of TGF‐β using mammary carcinoma cells to investigate the cooperation of mutant RAS proto‐oncogenes with TGF‐β in the induction of epithelial–mesenchymal transition (EMT) or enhanced cellular invasion, the stabilization of mammalian target of rapamycin signaling to retain the stemness of cells by prolonged TGF‐β exposure, and the collaboration with jun B proto‐oncogene (JUNB) to enhance cell invasion [17, 18, 19, 20]. This evidence concerns the gene TGFB1 and breast carcinoma.