IL1RN and bacterial infectious disease: In addition, further analysis of the bacterial infections (either Gram-positive (n = 32) or Gram-negative BSI (n = 24)) showed that the IL1RN*2 allele was associated with a decreased risk of Gram-negative BSI (unadjusted: HzR; 0.29, CI; 0.10–0.85; p-value; 0.025, adjusted: HzR; 0.31, CI; 0.11–0.88; p-value; 0.029).